Distinguished Professor, Department of Government
Department of Mathematics & Statistics,
Founding Director, Center for Data Science
Member, Center for Neuroscience and Behavior

American University, 4400 Massachusetts Avenue, NW, Washington, DC 20016

Controlling Phlebotomy Volume Diminishes PICU Transfusion: Implementation Processes and Impact

  • Steffen, Katherine, Allan Doctor, Julie Hoerr, Jeff Gill, Chris Markham, Sarah M. Brown, Daniel Cohen, et al. “Controlling Phlebotomy Volume Diminishes PICU Transfusion: Implementation Processes and Impact”. Pediatrics 140, no. 2 (2017)

    BACKGROUND AND OBJECTIVES: Phlebotomy excess contributes to anemia in PICU patients and increases the likelihood of red blood cell transfusion, which is associated with risk of adverse outcomes. Excessive phlebotomy reduction (EPR) strategies may reduce the need for transfusion, but have not been evaluated in a PICU population. We hypothesized that EPR strategies, facilitated by implementation science methods, would decrease excess blood drawn and reduce transfusion frequency. METHODS: Quantitative and qualitative methods were used. Patient and blood draw data were collected with survey and focus group data to evaluate knowledge and attitudes before and after EPR intervention. The Consolidated Framework for Implementation Research was used to interpret qualitative data. Multivariate regression was employed to adjust for potential confounders for blood overdraw volume and transfusion incidence.

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